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中国科学院上海巴斯德研究所 广州市妇女儿童医疗中心感染与免疫联合研究中心 博士后招聘启事
发布时间:2017-12-07

一.博士后联合培养项目简介

中国科学院上海巴斯德研究所—广州市妇女儿童医疗中心感染与免疫联合研究中心(以下简称“联合中心”)博士后联合培养项目依托中国科学院上海巴斯德研究所(简称上海巴斯德所)生物学博士后流动站和广州市妇女儿童医疗中心(简称广州妇儿中心)博士后工作站共同设立,现面向全球招收高水平博士后。

该项目将充分发挥广州妇儿中心的临床医学研究优势和上海巴斯德所的病原学、免疫学基础研究优势及国际网络优势,培养转化医学研究的高层次人才。该项目采用双导师制,即工作站和流动站各配备一名导师,负责对博士后进行指导。工作地点根据项目研究的需要,一般需在上海和广州两方开展研究,以其中一方为主。

二.应聘条件

应聘者应具有PhD和/或MD学位,发表过高质量研究论文,国籍不限,35周岁以下。

三.待遇

年薪不低于21万元(含每月3000元租房补贴);一次性50万元研究基金资助;根据广州妇儿中心科研奖励制度,享受论文发表及基金立项的科研奖励。

四.招聘方向

序号

合作方向

流动站导师

工作站导师

1

肠道、生殖道微生物菌群动态变化对围绝经期疾病和绝经激素替代治疗的影响及相关分子机制研究

陈昌斌

何耀娟

2

生殖道微生物菌群和HPV的相互作用在生殖道癌前病变及癌变的进展中的作用及相关机制研究

陈昌斌

沈丽青

3

1. 肠炎过程中,免疫炎症信号的局部到系统免疫应答的“肠肝对话机制”2. 肠道固有免疫-菌群结构稳态-代谢调节之间的微环境平衡研究3.肠炎过程中,肠道通透性和免疫损伤机制

潘磊

龚四堂

4

脓毒症免疫应答及其机制研究

张晓明

武志远

5

关节炎和红斑狼疮等自身免疫病的T细胞免疫应答调控机理

冷启彬

曾华松

6

病毒感染促进I型糖尿病的T细胞免疫应答机理

冷启彬

刘丽

7

肿瘤或者炎症性疾病的新型免疫治疗技术开发

冷启彬

龚四堂

8

肠道菌群变化对乙肝病毒免疫反应的影响及相关分子机制

魏玉

徐翼

9

1)细胞自噬功能在溶酶体病发病的作用;2)溶酶体病突变体对自噬功能的影响

魏玉

黄永兰

10

生物信息学技术融合深度学习算法的组学数据挖掘

郝沛

梁会营(夏慧敏)

11

肺部感染和过敏的炎症机制研究

孟广勋

卢根

12

乙肝病毒转录调控的结构和功能机制及基于结构的新靶点的开发

王岚峰

徐翼

13

新生儿胆道闭锁的区域免疫病理机制研究

唐宏

夏慧敏

14

病毒性腹泻与肠道黏膜免疫和微生态失衡的机制研究

唐宏

龚四堂

15

自身炎症性疾病的天然免疫机制研究

孟广勋

曾华松

16

心脏损伤修复中干细胞的表观调控机制

张岩

段金柱

17

靶向心脏细胞的新型腺病毒载体研究及应用

周东明

段金柱

18

血小板在虫媒病毒感染中的相互作用和致病机制

Dimitri Lavillette

邓伟豪

19

区域免疫细胞的表观遗传和转录调控模式

郝沛

张玉霞

20

孕期寨卡病毒感染对胎盘发育的影响

Dimitri Lavillette

Gendie Lash

五.应聘申请

1.应聘材料:申请表(附件1),中英文简历两名推荐专家联系方式、辅助材料(包括:身份证复印件、学历学位证书复印件、获奖证书复印件、发表论文或授权专利证明等,合并为一个PDF文件)

2.请将应聘材料同时发送到电子邮箱:GIPrecruit@163.com和hrips@ips.ac.cn;并在邮件标题中注明“申请广上中心联合培养博士后职位+希望选择的导师姓名”。

3.联系电话:

广州市妇儿中心张老师020-38857693

中国科学院上海巴斯德所人事教育处郑老师021-54923045

4.申请截止时间:

本招聘启事从即日起至2018年2月28日有效。

六.机构简介

广州市妇女儿童医疗中心(以下简称“妇儿中心”)是一所医教研一体的三甲专科医院,核定床位数1,500张,是全国最大的儿童医院之一,其服务范围辐射华南六省以及港澳台和东南亚地区。妇儿中心年门诊达400万人次,年住院8万人次,年分娩1万8千人次。该中心设备先进,技术力量雄厚,学科齐全,其中,儿童呼吸科、儿童消化科及小儿外科为国家临床重点专科;产科、新生儿科、胎儿医学科、儿童口腔科及妇幼保健学为省临床重点专科;小儿遗传病研究实验室为省临床重点实验室。设有国家级博士后工作站,现有35个临床专科可进行博士后研究工作,在站博士后达40余人,研究生60余人。为加强儿医和妇产医学的转化医学研究,特设广州儿科研究所,以美国NIH的管理模式进行管理。该研究所已建立8个独立实验室,并预计于明年内达到20-25个独立实验室规模。该研究所拥有一批先进实验设备,包括动物活体双光子显微镜,共聚焦显微镜,多光谱流式分析(18)和分选(16)仪,LC-LC/MS等,并于近期增加包括小动物MRI等在内的一批大型仪器。妇儿中心与国内外多家知名院校及科研单位有紧密的合作关系包括美国UCSD,Yale大学,澳大利亚WEHI研究所,中山大学,中科院武汉病毒所、中科院上海巴斯德所等。

中国科学院上海巴斯德研究所(以下简称“上海巴斯德所”)是由中国科学院、上海市政府、法国巴斯德研究所三方共建的科学研究机构,是隶属于中国科学院,专注于重大传染病领域及相关学科的独立法人事业单位,是巴斯德国际网络成员,世卫组织非政府组织成员。上海巴斯德所面向国际科学前沿和国家战略需求,聚焦重大传染性疾病的致病机制和免疫病理规律等关键科学问题,开展基础与应用型研究,推动病原学、免疫学、疫苗学等学科的发展,以解决免疫治疗(抗体、疫苗等)的共性瓶颈技术问题为着力点,为公共卫生与公共安全提供科技支撑和解决方案。设有国家级博士后生物学流动站,博士生导师23名,各类千人计划5名,中科院百人计划19名,各类在学研究生200名。年经费总量近亿元,发表论文过百篇,疫苗抗体年均转化、技术服务收入近亿元。

IPS-CAS - Guangzhou Women and Children's Medical Center

Joint Research Center for Infection and Immunity

Postdoctoral Training Opportunity

1. Joint Post-doctoral Training Program

Institut Pasteur of Shanghai, Chinese Academy of Sciences (IPS) and Guangzhou Women and Children's Medical Center (GWCMC) established a Joint Research Center in Infection and Immunity two years ago. The Joint Center is now proudly launching the second call for postdoctoral fellow applications to the following positions of related research fields (Table).

This program focuses on translational medicine, and candidates who have good track record of high quality research in infection and immunology, or its related fields, are welcome to apply. This program features dual-mentorship from both IPS and GWCMC, in order to strengthen the translational aspect of the studies. The qualified post-doctorates will be awarded with a research fund (equivalent to 75,000 USD), a salary of no less than 31500 USD, and productivity-based cash incentives.

Eligibility: Candidates should possess a recent PhD or MD degree, be under the age of 35, self-motivated, and fluent in English. There is no restriction to nationality and people from any minority are also encouraged to apply.

Table 1. Positions and mentors:

No

Research Fields(Topics)

Mentors (IPS-CAS)

Mentors (GWCMC)

1

Mechanistic studies of how dynamic changes in genital and gastrointestinal tract microbiota affect perimenopausal disease development and menopause hormone replacement therapy

Changbin Chen

Yaojuan He

2

Interplay between genital tract microbiota and HPV and its effect on precancerous lesions of the female genital tract and progress of carcinogenesis

Changbin Chen

LiqingShen

3

Organ to organ immune communication during IBD; Crosstalk among intestinal innate immunity, commensal microflora and the fat/energy metabolism; Pathogenic mechanisms of enteritis including not limit to intestinal permeability and immune damages

Lei Pan

Sitang Gong

4

Immune responses and regulatory mechanisms in pediatric sepsis

Xiaoming Zhang

Zhiyuan Wu

5

The molecular regulation of T cell-mediated inflammatory diseases, such as arthritis and lupus

Qibin LENG

HuasongZeng

6

How virus infections trigger autoreactive T cells that cause type I diabetes.

Qibin LENG

Li Liu

7

Develop novel immunotherapies against cancers or inflammatory diseases

Qibin LENG

Sitang Gong

8

Microbiota in immune response to hepatitis B virus infection

Yu WEI

Yi XU

9

Interplay between lysosomal dysfunction disease and autophagy

Yu WEI

Yonglan HUANG

10

Apply deeping learning in Bioiformatics to omics data mining

Pei Hao

Huiying Liang

11

Inflammatory mechanism study for infection and allergy in the lung

GuangxunMeng

Gen Lu

12

The structural and functional mechanism of Hepatitis B virus replication and structure based new drug target design.

Lanfeng Wang

Yi Xu

13

Immune Pathogenesis ofCongenital Biliary Atresia in newborns

HonTANG

Hui-min XIA

14

Immune Pathogenesis and Dysbiosisof Viral Diarrhea

HongTANG

Si-tang Gong

15

Innate mechanism study for autoinflammatory diseases

Guangxun Meng

Huasong Zeng

16

Epigenetic regulation of stem cells for cardiac injury

Yan Zhang

JinzhuDuan

17

New adenoviral vector targeting cardiac repair

Dongming Zhou

JinzhuDuan

18

Study the interaction between arboviruses and platelets and its role in the pathogenesis

Dimitri Lavillette

WeiHao Deng

19

Epigenetic and tracriptional regulation of tissue resident immune cells in paediatric diseases

Pei Hao

Yuxia Zhang

20

Impact of Zika virus infection on placental function during pregnancy

Dimitri Lavillette

Gendie Lash

Job Application

a. Application materials:

-Application Form (Appendix 1)

-CV in English

-Two recommendation letters or contact information including phone and e-mail of two references

-Additional materials (including: copy of ID, copy of academic degree certificate, a copy of award certificate, issued patents or published papers etc. into a single PDF file)

Please send e-mail to:GIPrecruit@163.com andhrips@ips.ac.cn, and write "Joint Postdoctoral Training Program + name of selected mentor" in the message object.

b. Contact:

Guangzhou Women and Children Center: Ms. Zhang +86 -20-38857693,

IPS-CAS Human Ressources Department : Ms.Zheng +86-21-54923045

c. Application deadline:

28th February2017

2. Brief Introduction of the Parties

a.Guangzhou Women and Children Medical Center

Guangzhou Women and Children’s Medical Center (GWCMC) was established in 2006, integrating the former Guangzhou Children’s Hospital and former Guangzhou Maternity Health Care Center. Covering an area of 37 thousand square meters and a built-up area of 130 thousand square meters, the hospital is equipped with 1,500 beds. Among the 2,603 staff, 282 is holding senior titles, 573 has received master level education or above and 47 of them are MD or MS mentors. The Hospital has greatly enhanced its capacity building. By now, two specialties have been honorably recognized as National Key Clinical Specialties entitled by the Ministry of Health, six as Guangdong Key Clinical Disciplines or Specialties, and one as Key Medical Laboratories listed in Guangdong “12th Five Year Plan”. It has been authorized to set up National Post-Doctoral Research Station. Affiliated Guangzhou Medical University, it also serves as a teaching, training and internship base for Sun Yat-sen University, South China Medical University and Jinan University Graduate School.

The hospital has evolved to be a high-level, comprehensive and multi-disciplinary health care institution, integrating the function of medical and healthcare, prevention, research and education.

b.Institut Pasteur of Shanghai – Chinese Academy of Sciences

Institut Pasteur of Shanghai – Chinese Academy of Sciences (IPS-CAS) is a scientific research institute founded in 2004 by the Chinese Academy of Sciences, the Shanghai Municipal Government, and the Institut Pasteur in Paris. It is a member of the Institut Pasteur International Network (IPIN), the WHO and other NGOs. IPS-CAS creates synergies between the Institut Pasteur and CAS networks, leveraging all the assets of Shanghai as one of Asia’s leading business and technology hubs. Our scientists are engaged in a broad range of infectious disease research programs ranging from viral hepatitis, HIV, respiratory infections to virus-induced cancers.

IPS-CAS is in an ideal strategic position to conduct research and development in life sciences in China. Together with its academic and industry partners, IPS’s goal is to develop product candidates in the field of diagnostics, vaccines and therapeutics.